Adeno-associated virus (AAV) vectors are essential in gene therapy, but accurate and consistent quantification can be challenging — especially across serotypes and sample types.
This application note presents a total capsid quantification workflow using the Amperia™ platform, combining sensor-based detection with high-affinity capture reagents. With broad serotype coverage and performance in both crude and purified material, the method supports confident quantification throughout development.
Highlights
- Compatible with AAV1–AAV9 and AAVrh10
- Performs well in crude lysates and clarified samples
- Powered by Thermo Fisher CaptureSelect™ antibodies
- Run on the Amperia™ platform with guided setup and analysis
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Tags: AAV, Viral Vectors, Gene Therapy, Total Capsid